Season 1

Season One consists of 22 episodes that aired in the United States beginning September 13, 2005, and ending May 4, 2008. The first sixteen episodes aired on Tuesdays at 9:00 pm, after which the series was rescheduled to Thursdays.

Summary
After their mother's death in a suspicious fire about 22 years prior, Sam and Dean Winchester live a life on the road with their father as they grow up. Years pass and the boys team up to find their father, John Winchester, who went missing on a hunting trip. However, their father is not a typical hunter, he hunts supernatural creatures like ghosts, vampires, and spirits. He trained his sons to do the same. Along the way, Sam and Dean save innocent people, fight creatures and ghosts, and collect clues to their father's whereabouts. Sam begins to mysteriously develop psychic abilities and visions as they travel. With the help of an old close family friend of theirs, the boys eventually find their father, who reveals that the creature that killed Sam and Dean's mother years earlier is the yellow-eyed demon and the thing that can kill him is a legendary gun created by Samuel Colt.

Main Cast

 * Jared Padalecki as Sam Winchester (22/22)
 * Jensen Ackles as Dean Winchester (22/22)

Recurring Cast

 * Jeffrey Dean Morgan as John WInchester (8/22)
 * Jeffrey Dean Morgan as Azazel (1/22)
 * Nicki Aycox as Meg (4/22)
 * Nicki Aycox as Meg Masters (1/22)
 * Samantha Smith as Mary Winchester (2/22)
 * Adrianne Palicki as Jessica Moore (2/22)
 * Sebastian Spence as Tom (2/22)
 * Jim Beaver as Bobby Singer (1/22)